Ureidopenicillin
From Wikipedia, the free encyclopedia
The ureidopenicillins are a group of penicillins which are active against Pseudomonas aeruginosa.
There are three ureidopenicillins in clinical use:[1]
They are mostly ampicillin derivatives in which the D-side amino chain has been converted to a variety of ureas. It is speculated that the added side chain mimics a longer segment of the peptidoglycan chain, more than ampicillin, and thus would bind more easily to the penicillin-binding proteins. Ureidopenicillins are not resistant to beta-lactamases.
They are used parenterally, and are particularly indicated in infections caused by Gram-negative bacteria.
[edit] References
- ^ "Mayo Clinic Proceedings". http://www.mayoclinicproceedings.com/inside.asp?AID=2547. Retrieved 2008-12-26.[dead link]
 |
This systemic antibacterial-related article is a stub. You can help Wikipedia by expanding it. |
|
