CSDA (genetics)

For other uses, see CSDA.

Cold shock domain protein A
PDB rendering based on 1h95.
Available structures PDB 1h95
Identifiers
Symbols	CSDA; CSDA1; DBPA; ZONAB
External IDs	OMIM: 603437 MGI: 2137670 HomoloGene: 2708 GeneCards: CSDA Gene
Gene Ontology Molecular function • DNA binding • double-stranded DNA binding • single-stranded DNA binding • sequence-specific DNA binding transcription factor activity • transcription corepressor activity • mRNA 3'-UTR binding Cellular component • nucleus • cytoplasm • polysome • gap junction Biological process • negative regulation of transcription from RNA polymerase II promoter • in utero embryonic development • transcription, DNA-dependent • regulation of transcription, DNA-dependent • spermatogenesis • male gonad development • response to cold • fertilization • organ regeneration • negative regulation of apoptosis • positive regulation of organ growth • negative regulation of skeletal muscle tissue development Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	8531	56449
Ensembl	ENSG00000060138	ENSMUSG00000030189
UniProt	P16989	Q8BPG0
RefSeq (mRNA)	NM_001145426.1	NM_011733
RefSeq (protein)	NP_001138898.1	NP_035863
Location (UCSC)	Chr 12: 10.85 – 10.88 Mb	Chr 6: 131.31 – 131.34 Mb
PubMed search	[1]	[2]

DNA-binding protein A is a protein that in humans is encoded by the CSDA gene.

Further reading

• Lloberas J, Soler C, Celada A (1998). "Repression mechanisms of the I-A beta gene of the major histocompatibility complex.". Immunobiology 198 (1-3): 249–63. PMID 9442396. 
• Kudo S, Mattei MG, Fukuda M (1995). "Characterization of the gene for dbpA, a family member of the nucleic-acid-binding proteins containing a cold-shock domain.". Eur. J. Biochem. 231 (1): 72–82. doi:10.1111/j.1432-1033.1995.tb20672.x. PMID 7628487. 
• Funke B, Zuleger B, Benavente R, et al. (1996). "The mouse poly(C)-binding protein exists in multiple isoforms and interacts with several RNA-binding proteins.". Nucleic Acids Res. 24 (19): 3821–8. doi:10.1093/nar/24.19.3821. PMC 146158. PMID 8871564. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=146158. 
• Weinmann AS, Yan PS, Oberley MJ, et al. (2002). "Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis.". Genes Dev. 16 (2): 235–44. doi:10.1101/gad.943102. PMC 155318. PMID 11799066. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=155318. 
• Hayashi J, Kajino K, Umeda T, et al. (2003). "Somatic mutation and SNP in the promoter of dbpA and human hepatocarcinogenesis.". Int. J. Oncol. 21 (4): 847–50. PMID 12239625. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Coles LS, Bartley MA, Bert A, et al. (2004). "A multi-protein complex containing cold shock domain (Y-box) and polypyrimidine tract binding proteins forms on the vascular endothelial growth factor mRNA. Potential role in mRNA stabilization.". Eur. J. Biochem. 271 (3): 648–60. doi:10.1111/j.1432-1033.2003.03968.x. PMID 14728692. 
• Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. 
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=514446. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Frankel P, Aronheim A, Kavanagh E, et al. (2005). "RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity.". EMBO J. 24 (1): 54–62. doi:10.1038/sj.emboj.7600497. PMC 544910. PMID 15592429. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=544910. 
• Tao WA, Wollscheid B, O'Brien R, et al. (2005). "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry.". Nat. Methods 2 (8): 591–8. doi:10.1038/nmeth776. PMID 16094384. 
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
• Sourisseau T, Georgiadis A, Tsapara A, et al. (2006). "Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA.". Mol. Cell. Biol. 26 (6): 2387–98. doi:10.1128/MCB.26.6.2387-2398.2006. PMC 1430269. PMID 16508013. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1430269. 
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 

External links

• MeSH CSDA+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.