ZNF259

Zinc finger protein 259
Identifiers
Symbols	ZNF259; MGC110983; ZPR1
External IDs	OMIM: 603901 MGI: 1330262 HomoloGene: 2900 GeneCards: ZNF259 Gene
Gene Ontology Molecular function • zinc ion binding • metal ion binding Cellular component • nucleus • nucleolus • cytoplasm Biological process • signal transduction • cell proliferation Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8882	22687
Ensembl	ENSG00000109917	ENSMUSG00000032078
UniProt	O75312	Q3TI08
RefSeq (mRNA)	NM_003904	NM_011752.2
RefSeq (protein)	NP_003895	NP_035882.1
Location (UCSC)	Chr 11: 116.65 – 116.66 Mb	Chr 9: 46.08 – 46.09 Mb
PubMed search	[1]	[2]

Zinc finger protein ZPR1 is a protein that in humans is encoded by the ZNF259 gene.

Further reading

• Gangwani L, Mikrut M, Galcheva-Gargova Z, Davis RJ (1999). "Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells.". J. Cell Biol. 143 (6): 1471–84. doi:10.1083/jcb.143.6.1471. PMC 2132977. PMID 9852145. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2132977. 
• Moores SL, Selfors LM, Fredericks J, et al. (2000). "Vav family proteins couple to diverse cell surface receptors.". Mol. Cell. Biol. 20 (17): 6364–73. doi:10.1128/MCB.20.17.6364-6373.2000. PMC 86111. PMID 10938113. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=86111. 
• Narayanan U, Ospina JK, Frey MR, et al. (2003). "SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta.". Hum. Mol. Genet. 11 (15): 1785–95. doi:10.1093/hmg/11.15.1785. PMC 1630493. PMID 12095920. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1630493. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Gangwani L, Flavell RA, Davis RJ (2005). "ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies.". Mol. Cell. Biol. 25 (7): 2744–56. doi:10.1128/MCB.25.7.2744-2756.2005. PMC 1061650. PMID 15767679. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1061650. 
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
• Guo D, Han J, Adam BL, et al. (2005). "Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress.". Biochem. Biophys. Res. Commun. 337 (4): 1308–18. doi:10.1016/j.bbrc.2005.09.191. PMID 16236267. 
• Gangwani L (2007). "Deficiency of the zinc finger protein ZPR1 causes defects in transcription and cell cycle progression.". J. Biol. Chem. 281 (52): 40330–40. doi:10.1074/jbc.M608165200. PMID 17068332. 

External links

• MeSH ZNF259+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.