Safrazine

Safrazine
Systematic (IUPAC) name
	[3-(1,3-benzodioxol-5-yl)-1-methyl-propyl]hydrazine
Clinical data
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral
Identifiers
CAS number	33419-68-0
ATC code	None
PubChem	CID 34042
ChemSpider	31375
UNII	F5G0P5378C
Synonyms	4-benzo[1,3]dioxol-5-ylbutan-2-ylhydrazine; [3-(3,4-(methylenedioxy)phenyl)-1-butyl]hydrazine; 2-piperonylisopropylhydrazine
Chemical data
Formula	C11H16N2O2
Mol. mass	208.26 g/mol

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Safrazine (Safra) is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used introduced as an antidepressant in the 1960s, and is still used in Japan today.^[1]^[2]

[edit] See also

^ Yokoyama T, Karube T, Iwata N (January 1989). "Comparative studies of the effects of RS-8359 and safrazine on monoamine oxidase in-vitro and in-vivo in mouse brain". The Journal of Pharmacy and Pharmacology 41 (1): 32–6. PMID 2565961.
^ Inoue T, Izumi T, Honma H, et al. (1996). "[Survey and treatment strategy of antidepressant-resistant depression]" (in Japanese). Seishin Shinkeigaku Zasshi = Psychiatria Et Neurologia Japonica 98 (5): 329–42. PMID 8741286.

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