Dexetimide

Dexetimide
Systematic (IUPAC) name
	3-(1-benzyl-4-piperidyl)-3-phenylpiperidine-2,6-dione
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	21888-98-2
ATC code	N04AA08
PubChem	CID 30843
ChemSpider	28615
UNII	43477QYX3D
KEGG	D03711
ChEMBL	CHEMBL273974
Chemical data
Formula	C23H26N2O2
Mol. mass	362.465 g/mol
SMILES	eMolecules & PubChem
	InChI InChI=1S/C23H26N2O2/c26-21-11-14-23(22(27)24-21,19-9-5-2-6-10-19)20-12-15-25(16-13-20)17-18-7-3-1-4-8-18/h1-10,20H,11-17H2,(H,24,26,27)/t23-/m1/s1 ; Key:LQQIVYSCPWCSSD-HSZRJFAPSA-N ;
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Dexetimide is a piperidine anticholinergic. It is a muscarinic antagonist that has been used to treat neuroleptic-induced Parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968.^[1]^[2]

[edit] References

^ Dom, R.; Van Lommel, R.; Baro, F. (1971). "A quantitative study of neuroleptic-induced extrapyramidal symptoms and their response to dexetimide, a potent and long-acting antiparkinsonian agent". Acta psychiatrica Scandinavica 47 (4): 399–410. PMID 4947805. edit
^ Huygens, H.; Vereecken, J. L.; Tanghe, A. (1973). "Dexetimide (R 16470) in the control of neuroleptic-induced extrapyramidal side-effects. Its prophylactic value and duration of action". Psychiatria, neurologia, neurochirurgia 76 (4): 251–259. PMID 4581374. edit

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