4-Benzylpiperidine
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| Systematic (IUPAC) name | |
| 4-(phenylmethyl)piperidine | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 31252-42-3 |
| ATC code | ? |
| PubChem | CID 31738 |
| ChemSpider | 29432  |
| ChEMBL | CHEMBL144129 |
| Chemical data | |
| Formula | C12H17N |
| Mol. mass | 175.270 g/mol |
| SMILES | eMolecules & PubChem |
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4-Benzylpiperidine is a drug and research chemical used in scientific studies. It acts as a monoamine releasing agent with 20- to 48-fold selectivity for releasing dopamine versus serotonin.[1] It has a fast onset of action and a short duration.[1] It also functions as a monoamine oxidase inhibitor (MAOI) with preference for MAO-A.[2]
[edit] See also
[edit] References
- ^ a b Negus SS, Baumann MH, Rothman RB, Mello NK, Blough BE. (2009). "Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine.". J Pharmacol Exp Ther. 329 (1): 272–281. doi:10.1124/jpet.108.143701. PMC 2670586. PMID 19151247. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2670586.
- ^ Arai Y, Hamamichi N, Kinemuchi H. (1986). "Time-dependent inhibition of rat brain monoamine oxidase by an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine.". Neurosci Lett. 70 (2): 255–260. doi:10.1016/0304-3940(86)90473-8. PMID 3490636.
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