Cannabinol
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| Systematic (IUPAC) name | |
| 6,6,9-trimethyl-3-pentyl-benzo[c]chromen-1-ol | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 521-35-7  |
| ATC code | ? |
| PubChem | CID 2543 |
| IUPHAR ligand | 740 |
| ChemSpider | 2447 |
| UNII | 7UYP6MC9GH |
| KEGG | C07580 |
| ChEMBL | CHEMBL74415 |
| Chemical data | |
| Formula | C21H26O2 |
| Mol. mass | 310.43 g/mol |
| SMILES | eMolecules & PubChem |
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- Not to be confused with Cannabidiol, a cannabinoid that is less psychoactive and which is sometimes erroneously called/pronounced 'Cannabinol'.
Cannabinol (CBN) is a psychoactive substance cannabinoid found in Cannabis sativa and Cannabis indica/afghanica.[1] It is also a metabolite of tetrahydrocannabinol (THC).[2] CBN acts as a weak agonist of the CB1 and CB2 receptors, with lower affinity in comparison to THC.[3][4]
[edit] See also
[edit] References
- ^ Karniol IG, Shirakawa I, Takahashi RN, Knobel E, Musty RE (1975). "Effects of delta9-tetrahydrocannabinol and cannabinol in man". Pharmacology 13 (6): 502–12. doi:10.1159/000136944. PMID 1221432.
- ^ McCallum ND, Yagen B, Levy S, Mechoulam R (May 1975). "Cannabinol: a rapidly formed metabolite of delta-1- and delta-6-tetrahydrocannabinol". Experientia 31 (5): 520–1. PMID 1140243.
- ^ Mahadevan A, Siegel C, Martin BR, Abood ME, Beletskaya I, Razdan RK (October 2000). "Novel cannabinol probes for CB1 and CB2 cannabinoid receptors". Journal of Medicinal Chemistry 43 (20): 3778–85. doi:10.1021/jm0001572. PMID 11020293.
- ^ Petitet F, Jeantaud B, Reibaud M, Imperato A, Dubroeucq MC (1998). "Complex pharmacology of natural cannabinoids: evidence for partial agonist activity of delta9-tetrahydrocannabinol and antagonist activity of cannabidiol on rat brain cannabinoid receptors". Life Sciences 63 (1): PL1–6. doi:10.1016/S0024-3205(98)00238-0. PMID 9667767. http://linkinghub.elsevier.com/retrieve/pii/S0024320598002380.
[edit] External links
- Erowid Compounds found in Cannabis sativa
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