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Talipexole

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Talipexole
Systematic (IUPAC) name
6-allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status Prescription only
Routes Oral
Identifiers
ATC code None
PubChem CID 5374
UNII 7AM2J46Z1Y N
ChEMBL CHEMBL1289023 N
Chemical data
Formula C10H15N3S 
Mol. mass 209.31 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Talipexole (B-HT920) is a dopamine agonist that has been proposed as an antiparkinsonian agent.[1] It also has α1-adrenergic and α2-adrenergic agonist activity.[2]

[edit] References

  1. ^ Kitamura Y, Kosaka T, Kakimura JI, et al. (December 1998). "Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic death in human neuroblastoma SH-SY5Y cells". Mol. Pharmacol. 54 (6): 1046–54. PMID 9855633. http://molpharm.aspetjournals.org/cgi/pmidlookup?view=long&pmid=9855633. 
  2. ^ Van der Laan JW (February 1987). "Dopaminergic and alpha 1-adrenergic properties of B-HT920 revealed in morphine-dependent rats". Pharmacology, Biochemistry, and Behavior 26 (2): 265–9. doi:10.1016/0091-3057(87)90116-X. PMID 2883663. 



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