Iodocyanopindolol

Iodocyanopindolol
Systematic (IUPAC) name
	(RS)-4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3-iodo-1H-indole-2-carbonitrile
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	85124-14-7
ATC code	None
IUPHAR ligand	540
Chemical data
Formula	C16H20IN3O2
Mol. mass	413.25 g/mol
SMILES	eMolecules & PubChem
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Iodocyanopindolol (INN) is a drug related to pindolol which acts as both a β₁ adrenoreceptor antagonist and a 5-HT_1A receptor antagonist. Its ¹²⁵I radiolabelled derivative has been widely used in mapping the distribution of beta adrenoreceptors in the body.^[1]

[edit] References

^ Brodde OE, Karad K, Zerkowski HR, Rohm N, Reidemeister JC (1983). "Coexistence of beta 1- and beta 2-adrenoceptors in human right atrium. Direct identification by (+/-)-[125I]iodocyanopindolol binding". Circulation Research 53 (6): 752–758. PMID 6139182.

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