ABT-670
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| Systematic (IUPAC) name | |
| 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| ATC code | ? |
| PubChem | CID 16094676 |
| ChemSpider | 17252978  |
| ChEMBL | CHEMBL219182 |
| Chemical data | |
| Formula | C19H23N3O2 |
| Mol. mass | 325.404 g/mol |
| SMILES | eMolecules & PubChem |
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ABT-670 is a drug which acts as a potent, orally bioavailable dopamine agonist selective for the D4 subtype, which was developed as a possible treatment for erectile dysfunction,[1] although its current uses are limited to scientific research.[2]
[edit] See also
- ABT-724
- Bremelanotide
- Cabergoline
- Flibanserin
- Intrinsa
- Melanotan II
- Pramipexole
- PF-219,061
- Tibolone
- UK-414,495
[edit] References
- ^ Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD et al. (2006). "Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-2,4'-bipyridine-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction". Journal of medicinal chemistry 49 (25): 7450–65. doi:10.1021/jm060662k. PMID 17149874.
- ^ Richards N, Wayman C, Allers KA. Electrophysiological actions of the dopamine agonist apomorphine in the paraventricular nucleus during penile erection. Neuroscience Letters. 3 September 2009 doi:10.1016/j.neulet.2009.08.078
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