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Enilospirone

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Enilospirone
Systematic (IUPAC) name
6-(3-chlorophenoxy)-2-methyl-1-oxa-4-azaspiro[4.5]decan-3-one
Clinical data
Pregnancy cat.  ?
Legal status Uncontrolled
Routes Oral
Identifiers
CAS number 59798-73-1
ATC code None
PubChem CID 68794
ChemSpider 62034
UNII WO31V62797 YesY
Chemical data
Formula C15H18ClNO3
Mol. mass 295.76 g/mol

Enilospirone (CERM-3,726) is a selective 5-HT1A receptor agonist of the azapirone class.[1]

[edit] See also

[edit] References

  1. ^ Maurel JL, Autin JM, Funes P, Newman-Tancredi A, Colpaert F, Vacher B (October 2007). "High-efficacy 5-HT1A agonists for antidepressant treatment: a renewed opportunity". Journal of Medicinal Chemistry 50 (20): 5024–33. doi:10.1021/jm070714l. PMID 17803293. 

[edit] Further reading

  • Nicholson AN, Stone BM (1982). "6-(3-chloro)-phenoxy-2-methyl-1-oxa-4-azospiro-[4,5]decane-3-one (CERM 3726) and sleep of healthy men". Psychopharmacology 76 (2): 157–9. doi:10.1007/BF00435270. PMID 6805026. 


v · d · eAnxiolytics (N05B)
GABAA PAMs
Others
α2δ VDCC Blockers
5-HT1A Agonists
Azapirones: Buspirone • Gepirone • Tandospirone; Others: Flesinoxan • Oxaflozane
H1 Antagonists
Diphenylmethanes: Captodiame • Hydroxyzine; Others: Brompheniramine • Chlorpheniramine • Pheniramine
CRH1 Antagonists
NK2 Antagonists
MCH1 antagonists
mGluR2/3 Agonists
mGluR5 NAMs
TSPO agonists
σ1 agonists
Others

M: PSO/PSI

dsrd (o, p, m, p, a, d, s), sysi/epon, spvo

proc(eval/thrp), drug(N5A/5B/5C/6A/6B/6D)


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