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Lubazodone

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Lubazodone
Systematic (IUPAC) name
(2S)-2-[(7-fluoro-2,3-dihydro-1H-inden-4-yl)oxymethyl]morpholine
Identifiers
CAS number 161178-07-0
ATC code none
PubChem 157919
Chemical data
Formula C14H18FNO2 
Mol. mass 251.296 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Lubazodone (YM-992, YM-35,995) is a psychoactive drug and research chemical which was being developed as an antidepressant. It functions as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist. Lubazodone made it to phase II clinical trials but was discontinued in 2001, apparently due to the erosion of the selective serotonin reuptake inhibitor (SSRI) market in the United States.

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v • d • e
Psychoanaleptics: antidepressants (N06A)
SSRIs
SNRIs
NRIs
NDRIs
DRIs
SNDRIs
SSREs
NDRAs
TCAs
TeCAs
MAOIs
Direct
Receptor
Ligands
Dietary
Supplements
Amino Acids/Precursors: 5-HTP • L-DOPA • L-Glutamine • L-Phenylalanine • L-Tryptophan • L-Tyrosine
Vitamins/Minerals: Ascorbic Acid (Vitamin C) • B-Vitamins (Folic Acid, Niacin, Pyridoxal Phosphate, etc) • Magnesium • Zinc
Herbs: Curcuma Longa (Turmeric) • Eleutherococcus Senticosus (Siberian Ginseng) • Ginkgo Biloba (Ginkgo) • Glycyrrhiza Glabra (Licorice) • Hydrocotyle Asiatica (Gotu Kola) • Hypericum Perforatum (St John's Wort) • Panax Ginseng (Ginseng) • Passiflora Incarnata (Passion Flower) • Piper Methysticum (Kava Kava) • Peganum Harmala (Syrian Rue) • Rhodiola Rosea (Golden Root) • Rosmarinus Officinalis (Rosemary) • Sceletium Tortuosum (Kanna) • Schisandra Chinensis (Magnolia Vine) • Scutellaria Lateriflora (Skullcap) • Valeriana Officinalis (Valerian) • Zingiber Officinale (Ginger)
Others: Inositol • Omega-3 Fatty Acids • S-Adenosyl-L-Methionine (SAMe)
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