Environmental health science and environmental medicine comprise many fields
of study; therefore, EHP will consider scientific progress in all fields.
Cross-fertilization and serendipity have proven to be extremely important in
the advancement of science in general, and this must hold true for the environmental
health sciences. EHP will consider articles from a wide range of scientific
disciplines encompassing the most basic research to the most innovative technologies.
Researchers concerned with mechanisms of toxicity, new approaches for detecting
or remedying environmental damage, and the identification and characterization
of genes involved in the manifestation of environmentally related disease are
particularly encouraged to submit. EHP recognizes the vital interconnection
between the environment and human health. Physicians and others working in
environmental medicine are encouraged to submit reports for publication in
the Environmental Medicine Section. EHP also addresses ethical,
legal, social, and policy issues.
Scientific debate can lead to new research and discoveries. Opinions and
ideas based on scientific observations are welcome for publication in all EHP editions.
The formats available for publication include editorials and commentaries.
In either format, EHP strives for objectivity and balance.
Competing
Financial Interests
EHP has a long-standing requirement for authors to disclose competing
financial interests. Corresponding authors are required to submit with the
manuscript a declaration of competing financial interests on behalf of all
authors. When in doubt about the need to report, authors should always err
on the side of caution and report all interests that might in any way be
perceived as representing a competing financial interest. The form is available
online and can be downloaded (http://ehp.niehs.nih.gov/cfi.pdf).
If the article is accepted for publication, the statements are published
with the article disclosing either a competing financial interest, along
with a brief description, or a declaration of no competing interests.
Competing financial interests may include, but are not limited to, grant
support, employment (recent, present, or anticipated), patents (including
pending or applied for), payment for expert testimony, and personal financial
interests by the authors, immediate family members, or institutional affiliations
that may gain or lose financially through publication. Increasingly, researchers
are compensated through a host of financial arrangements such as travel funding,
consultancies, advisory board positions, patent and royalty arrangements,
stock shares, bonds, and the like. Diversified mutual funds or investment
trusts do not constitute a competing financial interest. Further, authors
are required to certify that their freedom to design, conduct, interpret,
and publish research is not compromised by any controlling sponsor as a condition
of review and publication.
Scientists are aware of the absolute necessity to maintain the personal
integrity upon which science depends. It is this integrity that full disclosure
of competing financial interests hopes to preserve. Therefore, it is imperative
that authors and readers understand that a disclosure of a competing financial
interest does not imply that the information in the article is questionable
or that the conclusions are biased. Authors must also understand that the
omission of a pertinent financial interest could, if later revealed, deal
a severe blow to the authors’ integrity and the credibility of their
research.
Our full disclosure policy was established because we are mindful of our
obligation to provide responsible and effective oversight to manuscripts
published in the journal. We believe it is vital for EHP to ensure
that information published in the journal is presented in an objective and
balanced manner, and that readers have the opportunity to judge for themselves
whether bias has been introduced because of any competing financial interests
of the authors. EHP’s policy of disclosure applies to research
articles, commentaries, reviews, and correspondence. Although full disclosure
is important, we believe that the decision to publish an article should not
be based on a declaration of a competing financial interest.
Our requirements for full disclosure also extend to reviewers and editors,
who must disclose to the editor-in-chief any competing financial interests
that could be construed as affecting their evaluation of a manuscript. Reviewers
and editors are not automatically disqualified because of a competing financial
interest. However, reviewers or editors might be asked to recuse themselves
when appropriate.
As is the case for most journals, EHP is not in the position to confirm
the accuracy of disclosure statements made by our authors. We rely on the
veracity of the authors, but EHP authors can expect scrutiny of their
statements by EHP readers and the authors’ own employers. EHP welcomes
this assistance and will publish letters to the editor that address alleged
inaccuracies of competing financial interest declarations. For authors who
willfully fail to disclose a competing financial interest, a 3-year ban on
publication will be imposed. Implementation of the ban will be made in consultation
with our editorial board. If complete disclosure of possible conflicts would
have caused the journal to reject the manuscript, the article will be retracted.
If the article is not retracted but an ethical omission has occurred, an
Expression of Concern will be written, published in the journal, and added
to the online version of the article.
Originality
of Submission
Contributions submitted to any edition of
EHP must be original
works of the author(s) that have not been previously published (print or online)
or simultaneously submitted to another publication. Submitted manuscripts are
acknowledged upon receipt.
Peer
Review
Three reviewers submit comments on each manuscript. Authors are strongly
encouraged to submit the names and contact information (including e-mail
addresses) of experts in their field of study for addition to EHP’s
scientific reviewer database. Each reviewer is asked to complete the review
within three weeks. If a revision of the manuscript is required, the revised
manuscript must be received within six weeks of the request; the submission
will be cancelled at that time unless prior permission is obtained. Authors
must submit the revised manuscript and a letter responding to reviewers’ comments.
Publication
Date of Record
Research articles accepted for publication in
EHP will be appear initially
as author-supplied PDF files in the
EHP-in-Press section on our website
(
http: //www.ehponline.org)
within 24 hours of acceptance. The PDFs will not be corrected or copyedited.
The articles will be citable using the DOI (Digital Object Identifier) code.
The date the article is included on the website will be considered the publication
date of record. This process substantially reduces time to publication after
acceptance, thus enabling the establishment of priority. Publication in the
printed journal will occur as space permits.
Page
Charges
Authors will be required to pay page charges at the
current rate, which is now $85.00/page. The corresponding
author will receive one copy of the issue free of charge.
Reprints may be ordered at the time page proofs are reviewed.
Late reprint orders will incur an administrative fee.
Invited articles and correspondence are not subject to
page charges.
Extensive changes in the manuscript cannot be made at the
proof stage. Only minor changes such as spelling, grammar,
and referencing are to be requested. If new information has
become available after acceptance of the manuscript, an addendum
in proof can be included with the permission of the editor-in-chief.
Copyrights,
Reproduction, and Citations
EHP is a publication of the United States
government. Publication of EHP lies in the public
domain and is therefore without copyright. Research articles
from EHP may be used freely; however, articles
from the Environews Section of EHP may contain
photographs or figures copyrighted by other commercial
organizations and individuals that may not be used without
obtaining prior approval from both the EHP editors
and the holder of the copyright. Use of materials published
in EHP should be acknowledged (for example, “Reproduced
with permission from Environmental Health Perspectives”);
pertinent reference information should be provided for
the article from which the material was reproduced. For
further information, contact EHP Permissions
(ehponline@niehs.nih.gov).
A press release or press conference should not publicize
articles submitted to EHP until the article has
been published. To determine the date and coordinate press
activities, call 919-653-2582. If EHP plans
a press release on an article, a copy of the text will
be supplied to the authors as a courtesy.
Environmental
Health Perspectives Content
The journal is a forum for the expression of carefully
considered ideas and opinions based on scientific principles.
Three formats are offered:
Book Reviews are short critical evaluations
of recently published books. The editors select the books
and the reviewers.
Correspondence is encouraged. Opinions, perspectives,
and insight, commenting on articles published in EHP,
are welcome. EHP will allow the opportunity
for defense and clarification in response to critical comments.
Letters must be appropriately referenced.
Editorials offer opinions and ideas to focus
attention on important areas of environmental health and
to stimulate discussion of such topics. Our editors, editorial
board members, and guest editors contribute these statements.
The Environews Section provides up-to-date information
on important issues in environmental health, covering a
variety of areas including but not limited to policy, legislative,
and regulatory actions; innovative technologic and conceptual
research advances; conference and meeting summaries; and
emerging environmental problems. The Environews Section
disseminates scientific and related information in a manner
that is comprehensible and usable by an informed lay, medical,
or scientific audience. The Environews Section comprises
a variety of formats:
Forum articles are brief reports on topics such
as recent research advances, scientific meetings, policy
and legislative updates, and academic, industry, government,
and nongovernmental organization activities in environmental
health.
NIEHS News articles describe current and ongoing
intramural research programs of the NIEHS and the National
Toxicology Program, as well as profiles of extramural grantee
programs and research.
Focus articles are major investigative articles
on a wide range of national and international environmental
health topics.
Spheres of Influence articles present balanced
analyses of legal, regulatory, public policy, and social
aspects of environmental health.
Innovations articles describe new discoveries
or approaches in environmental health research, remediation,
monitoring, and public health policy.
Science Selections are brief summaries of selected
research articles published in the concurrent Research
Section of EHP.
Extramural Update is a dedicated forum for
the NIEHS Extramural Program to disseminate information
on the programs, meetings, and training opportunities sponsored
by this division of the NIEHS.
NCT Update is a dedicated forum for dissemination
of information on the programs, meetings, and training
opportunities of the National Center for Toxicogenomics
(NCT) at the NIEHS.
Submission
of News Information
EHP welcomes items of interest for inclusion
in the Environews Section of the journal. All items are
published subject to the approval of the editor-in-chief.
All submissions for this section should be sent to
ehpnews@niehs.nih.gov
or by mail to the attention of:
News Editor
Environmental Health Perspectives
National Institute of Environmental Health Sciences
Mail Drop EC-15
PO Box 12233
Research Triangle Park, NC 27709
USA
Research
Section
The Research Section of the journal offers five formats:
Research Articles are original manuscripts reporting scientific
research and discovery in the broad field of environmental health. Original
manuscripts on ethical, legal, social, and policy issues are also accepted
for this section. Research articles may come from any field of scientific
research, from the most basic molecular biology and biochemistry to atmospheric
physics, ecology, and engineering, as well as related fields of social
science and ethics. The criteria for publication are weighted toward quality
and environmental significance. Manuscripts are assessed according to their
originality, scientific merit, and experimental design, and evaluated for
conciseness, clarity, and presentation. EHP also attempts to address
certain ethical problems during the review process and requires assurances
that all human and animal subjects have been treated humanely and with
regard for the alleviation of suffering. Our review also considers scientific
integrity as part of the process. Papers that do not conform to word limits
will be returned to the author(s) for shortening before the review process
can begin; please see the section on word limits.
Commentaries present information and insight on a particular
topic. Factual data should be included to substantiate arguments. Abstracts
are required, and articles must be appropriately referenced.
Reviews are narrowly focused articles that emphasize recent
developments in a particular field of research. Lengthy historical perspectives
are not appropriate.
Meeting Reports are short synopses of conferences, symposia,
or workshops in which the scientific objectives and achievements of a meeting
are described.
Workgroup Reports are presentations by expert scientific committees
that include reviews of existing information and that summarize research
findings on specific topics, present new information, and recommend methods,
courses of action, or further research needs for the scientific community.
Environmental
Medicine Section
This section comprises articles on environmental causes of disease relevant
to clinical practice (focused on individual health) and public health practice
(focused on population and community health issues). The articles may report
on the clinical manifestations, causes, and medical and nonmedical management,
as well as the public health, legal, regulatory, and ethical issues surrounding
environmentally related disease. Four formats exist: Reviews, Research
Articles, Grand Rounds, and Case Reports. Articles that demonstrate the
application of research advances to a clinical or community practice setting
(translational research) are particularly encouraged. All articles published
in this section require a structured abstract; see “Manuscript Preparation
and Submission.” Authors are encouraged to include public health,
legal, and ethical issues.
Reviews in environmental medicine are focused articles that
emphasize recent developments in a specific area of environmental medicine.
Of particular interest are reviews that provide guidance on clinical approaches,
community health approaches, causes and risk factors for environmental
disease, and/or in-depth discussions of areas of uncertainty that could
benefit from well-designed research.
Research Articles must be of original research involving human
subjects. Observational epidemiologic studies and randomized clinical trials
that are relevant to the clinical or public health practice of environmental
medicine are particularly encouraged, as are studies from developing countries.
Grand Rounds in environmental medicine articles present discussions
of case presentations of patients or community health issues of relevance
to environmental exposures and environmental health. The format requires
that a case scenario be presented to illustrate the environmental issues
under consideration, followed by a discussion of the clinical and public
health implications of these issues. Observations from developing countries
are especially encouraged. Articles should be divided into an Abstract,
Case Presentation, Discussion, and Conclusion.
Case Reports differ from Grand Rounds articles in that the
diagnosis pertaining to the clinical presentation is not necessarily conclusive.
Instead, evidence for an environmental etiology may be indirect: for example,
a case report of hepatitis that is suspected to be related to a chemical
that had not been previously linked with hepatitis. Similar to Grand Rounds,
Case Reports should include an Abstract, Case Presentation, Discussion,
and Conclusion.
Children’s
Health Section
Children have unique vulnerability to environmental factors, and
EHP is
a pioneer in the dissemination of information on children’s environmental
health issues. This section contains contributions covering environmental
science, toxicology, risk assessment and management, pediatric environmental
medicine, social sciences, and legal and regulatory issues. Basic and applied
research is reported in this section in the form of Commentaries, Reviews,
Research Articles, Mini-Monographs, Meeting Reports, and Workgroup Reports.
Toxicogenomics
Section
The development of powerful molecular tools for
genomics research has provided an area of unprecedented
research for investigators in toxicology and environmental
health. Researchers in toxicogenomics conduct studies
to elucidate biological responses in the genome after
exposure to environmental toxicants and stressors.
This section of EHP focuses on the field of
toxicogenomics and extends to the related disciplines
of pharmacogenomics, proteomics, metabolomics, metabonomics,
molecular epidemiology, translational aspects of genomic
research, and molecular medicine. Basic and applied
research is reported in this section in the form of
Commentaries, Reviews, Research Articles, Mini-Monographs,
Meeting Reports, and Workgroup Reports.
Submissions to the Toxicogenomics Sectionmust follow
the guidelines based on the document called “Minimum
Information About a Microarray Experiment – MIAME,” developed
by the Microarray Gene Expression Data Society (http://www.mged.org/miame).
On acceptance, all integral data supporting the paper’s
conclusions should be submitted to the ArrayExpress
(http://www.ebi.ac.uk/arrayexpress)
or GEO (http://www.ncbi.nlm.nih.gov/geo/)
databases.
Mini-Monographs are published throughout the year as special
sections in the journal. Mini-Monographs consist of generally
up to six manuscripts that address a specific topic and
may include original research, perspective reviews, or
a combination of original research and review. These series
go beyond the limits of the traditional reviews by providing
insights and depth of coverage that a traditional review
article cannot.
Mini-Monographs are intended for researchers, teachers,
legislators, and the informed public. Mini-Monograph topics
may be proposed by a guest editor or selected by the editorial
board. Proposals submitted to the editor-in-chief are reviewed
for originality and scientific merit, apparent need for
the Mini-Monograph, timeliness of the subject matter, usefulness
to workers in the field, environmental significance, completeness
in covering the proposed topic, clarity of presentation,
and appropriateness and scientific credibility of the proposed
contributors.
Articles submitted for inclusion in a Mini-Monograph must
be of the same high scientific quality as required for
the regular monthly issues. However, research articles
may be of more limited scope when considered in the context
of the Mini-Monograph. Review articles may be of a broader
nature, providing summaries of new developments in environmentally
relevant areas, a balanced perspective for these new findings,
and inclusion of sufficient background information to accommodate
those not familiar with the specific topic.
Announcements include a calendar of upcoming events such
as conferences, workshops, and public hearings. Appropriate
listings are made for industrial, academic, regulatory,
and legal activities. This section also includes fellowship
announcements, grant announcements, positions available,
and a book review.
EHP Chinese-Language
Edition
EHP has expanded its international
presence by establishing a quarterly Chinese-Language
Edition. This edition includes original and previously
published Environews articles translated into Chinese.
It also includes Editorials written by scientists directly
involved in research in the Chinese-speaking areas of
the world.
Manuscript
Preparation and Submission
EHP covers all disciplines
engaged in the broad field of environmental health sciences.
Authors should therefore write in a clear and simple
manner, avoiding unnecessary jargon, so that the article
is understandable to readers in other disciplines.
Conformance
to EHP Style Requirements
Manuscripts submitted to EHP must conform to all EHP style
requirements. Authors should take special note of requirements
for citations/references, figures, and tables. Manuscripts
that do not conform will be returned to the authors for
modification before the initiation of the peer review process.
This step will cause a significant delay in the publication
of the manuscript.
The authors must ensure that the final PDF supplied to EHP is
accurate. Once the manuscript is accepted, the PDF will
be published online generally within 24 hours after acceptance.
Any substantive changes after this stage will require an
erratum to be published.
Manuscripts must be written in the active voice and be
typed double-spaced in English. Number pages consecutively,
beginning with the title page. Numbering of lines is preferred
but not required. The reference list, tables, and figure
legends should begin on separate pages and should also
be double-spaced.
Page one: The first page should list title,
authors (first or second names spelled out in full), full
address of the institution where the work was performed,
and affiliation of each author. Titles should not exceed
20 words and should generally not contain abbreviations
or numerical values. Indicate the author to whom page proofs
should be sent, and include complete address for express
mail service, telephone and fax numbers, and e-mail address.
Page two: 1) Place a running title, not to exceed
50 characters and spaces, on this page. 2) List on this
page 5–10 key words for indexing purposes. 3) Include
acknowledgments and grant information, not to exceed 50
words. 4) Include a list of all abbreviations with definitions
used in the manuscript. Nomenclature and symbols should
conform to the recommendations of the American Chemical
Society or the International Union of Pure and Applied
Chemistry.
Page three: Provide an outline of section
headers (i.e., abstract, introduction, methods, etc.) on
this page. This outline will facilitate copyediting and
manuscript layout.
Page four: All articles must include an abstract
not to exceed 250 words, which should be placed on this
page. Do not include references or details of the materials
and methods in the abstract.
All articles submitted for the Environmental Medicine
Section should include a structured abstract, not to exceed
250 words. No information should be reported in the abstract
that does not appear in the text of the manuscript
-
Structured abstracts for Reviews should have the headings
Objective, Data Sources, Data Extraction, Data Synthesis, and Conclusions.
-
Structured abstracts for Research Articles should have
the headings Objective, Design, Participants, Evaluations/Measurements,
Results, Conclusions, and Relevance to Clinical or Professional Practice.
-
Structured abstracts for Grand Rounds Articles or Case
Reports should have the following sections: Context (this is the relevance
to environmental exposures and environmental health), Case Presentation,
Discussion, and Relevance to Clinical or Professional Practice.
Page five and subsequent pages: Text should begin
on the fifth page. Concise headings (not to exceed eight words) may be used
to designate major sections. Recommended headings, where appropriate, are “Materials
and Methods,” “Results,” “Discussion” or “Conclusion,” and “References.” Do
not include tables and figures in the text. Place them after the References
section.
Article
Length
Editorials should not exceed 1,000 words including references. Correspondence
should not exceed 750 words and may include a brief table or small
figure; letters should be appropriately referenced. Commentaries should
not exceed 5,000 words, including tables, figures, and references.
Research Articles should not exceed 7,000 words, including tables,
figures, and references. Reviews and Workgroup Reports should not exceed
8,000 words, including tables, figures, and references. Meeting Reports
should not exceed 5,000 words, including tables, figures, and references.
The “Case Presentation” in Grand Rounds and Case Report
articles should be less than 1,000 words, and the remainder of the
paper should not exceed 5,000 words including tables, figures, and
references. Visual images (e.g., X rays, microscopic pathology) or
other graphics are encouraged. In determining the word count for all
submissions, assume each figure and table accounts for 250 words of
the total word count.
References/Citations/Footnotes
References and citations should be formatted according to
EHP style
(examples provided below). This will reduce copyediting time and the number
of author queries included in page proofs. Authors should double-check all
references for accuracy and completeness of information, spelling, accents,
symbols, subscripts and superscripts, and italics. Authors are fully responsible
for the accuracy of their references. Check the final draft to make sure
citations and references match. Any manuscript that is not properly formatted
will be returned to the author for correction before review.
Do not use footnotes; instead, place all textual information
within the manuscript and all citations/references in the
proper form.
Citations
All citations must be placed in name/date form. Place the citation immediately
after the textual information cited, placing name and date within parentheses
without a comma.
Single author: (Burkholder 1998) Two authors: (Burkholder
and Glasgow 1997) Three or more authors: Use first author’s
name plus “et al.” (Burkholder et al. 2001). Different
first authors but same last name and date: Use first author’s
last name plus initial(s) (Smith A 2000; Smith J 2000)
Several sources cited at one time: List
publications alphabetically by author in the
citation. Separate publications by the same author(s)
with commas and those by different authors with
semicolons: (Burkholder and Glasgow 1997a, 1997b;
Peal 1975; Wee 1997).
Quotations: Provide references for any quotations
used in the text. For example:
According to Rubin et al. (2001), “it is only
with a multidisciplinary and collaborative approach that the environmental
and public health significance of Pfiesteria will be fully
understood.”
All manuscripts submitted but not yet accepted, unpublished data, and
personal communications--any items that must be cited but are not
accessible to the public--must appear in the text in parentheses
but should not be listed in the references: (Ramsdell JS, Moeller PDR,
personal communication); (Glasgow HB, unpublished data).
References
Authors are fully responsible for the accuracy of their references.
The list of references should begin on a separate page. All references
must include
-
Author/editor last name plus initials (for six or fewer
authors; if there are more than six authors, use “et al.” after
the sixth) or authoring agency
-
Year of publication
-
Full title of article or chapter (lower case)
-
Title of journal (abbreviated according to Biosis or Index
Medicus) or book/proceedings in title case
-
City/state/country of publication and name of publisher
-
Volume and inclusive page numbers
-
DOI reference, if known.
If you are uncertain what to include, please include all information.
List references alphabetically by the last name of the first author. If
the first author has more than one publication, list references in alphabetical
order (letter by letter) of subsequent authors. If the first author shares
the last name with another first author (Smith JM vs. Smith RB), alphabetize
by initials. If you list more than one publication by the same author/group
of authors, arrange publications by date, early to late. If you list more
than one publication published in the same year by the same author/group
of authors, use a, b, c, d, and so on to distinguish the publications.
Sample alphabetical list:
Burkholder JM. 1998. Implications of harmful marine microalgae and heterotrophic
dinoflagellates in management of sustainable marine fisheries. Ecol Appl
8(suppl): S37–S62.
Burkholder JM, Glasgow HB. 1997a. Pfiesteria piscicida and other Pfiesteria-like
dinoflagellates: behavior, impacts, and environmental controls. Limnol
Oceanogr 42:1052–1075.
Burkholder JM, Glasgow HB. 1997b. Trophic controls on stage transformations
of a toxic ambush-predator dinoflagellate. J Eukaryot Microbiol 44:200–205.
Burkholder JM, Glasgow HB. In press. Toxic Pfiesteria in North
Carolina estuaries from 1991 to the present. BioScience.
Burkholder JM, Glasgow HB, Lewitus AJ. 1998. Physiological ecology of Pfiesteria
piscicida with general comments of “ambush-predator” dinoflagellates.
In: Physiological Ecology of Harmful Algae (Anderson DM, Cembella A,
Hallegraeff GM, eds). NATO ASI Series G: Ecological Sciences, Vol 41.
Berlin:Springer-Verlag, 175–191.
Burkholder JM, Mallin MA, Glasgow HB, Larsen LM, McIver MR, Shank GC,
et al. 1997. Impacts to a coastal river an estuary from rupture of a large
swine waste holding lagoon. J Environ Qual 26:1451–1466.
Types of references:
Journal article--conventional reference only
Burkholder JM, Glasgow HB. 1997. Pfiesteria
piscicida and other Pfiesteria-like dinoflagellates: behavior,
impacts, and environmental controls. Limnol Oceanogr 42:1052–1075.
Journal article--DOI reference only
Hightower JM. Mercury levels in high-end consumers of fish. Environ Health
Perspect doi:10.1289/EHP.5901 [Online 1 November 2002].
Journal article--conventional reference and DOI reference
Hu Y, Ippolito JE, Garabedian EM, Humphrey PA, Gordon JI. 2002. Molecular
characterization of a metastatic neuroendocrine cell cancer rising in the
prostates of transgenic mice. J Biol Chem 277:44462–44474; doi: 10.1074/jbc.M205784200
[Online 11September 2002].
Journal article, “in press”
Turusov V, Rakitsky V, Tomatis L. In press. Dichlorodiphenyltrichloroethane
(DDT); ubiquity, persistence, and risks. Environ Health Perspect.
Journal article, anonymous author
[Anonymous.] 1998. New source of fish fears.
Environ Health Perspect 106:A425–A426.
Journal article in non-English language
Rateau JG, Broillard M, Morgant G, Aymard P. 1986. Etude experimental chez
le lapin de l’effet de la cholestyramine dans le traitement des
diarrhees infectieuses d’orgine cholerique [in French]. Actualite
Therapeut 22: 289–296.
Magazine article
Grant M. 1997. The cell from hell. People, 19 May: 101–103.
Newspaper article
Clabby C. 2001. Study details how centuries of fishing depleted sea life.
News and Observer (Raleigh, NC) 27 July: B1.
Chapter in edited book
Wen L-S, Shiller A, Santschi PH, Gill G. 1999. Trace element behavior in
Gulf of Mexico estuaries. In: Biogeochemistry of Gulf of Mexico Estuaries
(Bianchi TS, Pennock JR, Twilley RR, eds). New York:John Wiley and Sons,
303–346.
Chapter in edited series
Burkholder JM, Glasgow HB, Lewitus AJ. 1998. Physiological ecology of Pfiesteria
piscicida with general comments of “ambush-predator” dinoflagellates.
In: Physiological Ecology of Harmful Algae (Anderson DM, Cembella A, Hallegraeff
GM, eds). NATO ASI Series G: Ecological Sciences, Vol 41. Berlin:Springer-Verlag,
175–191.
Agency monograph
IARC. 1982. Di(2-ethylhexyl)phthalate. IARC Monogr Eval Carcinog Risks
Hum 29:269–294.
Book
Luna LG. 1968. Manual of Histopathologic Staining Methods of the Armed
Forces Institute of Pathology. 3rd ed. New York:McGraw-Hill.
Book, edited
Gross TL, Ihrke PJ, Walder EJ, eds. 1992. Veterinary Dermatopathology.
St. Louis, MO:Mosby Year Book.
Agency as author
NCDENR. 1999. Annual Report of Fish Kill Events. Raleigh, NC:North Carolina
Department of Environment and Natural Resources.
Proceedings
Tiran B, Rossipal E, Tiran A, Lorenz O. 1993. Selenium and iodine concentration
in human milk and milk formulas in Styria, Austria. In: Proceedings of
the Conference on Trace Elements in Man and Animals: TEMA 8, 16–21
May 1993, Dresden, Germany. Gersdorf, Germany:Verlag Media Touristik,
1058–1061.
Technical paper
NTP. 1998. Toxicology and Carcinogenesis Studies of Diethanolamine (CAS
No. 111-42-2) in F344/N Rats and B6C3F1 Mice (Dermal
Studies). Technical Report 478. Research Triangle Park, NC:National Toxicology
Program.
Dissertation/thesis
Xi D. 1996. Mechanisms of Maitotoxin and Domoic Acid Action to Elevate
Cytosolic Free Calcium [PhD Thesis]. Charleston, SC:Medical University
of South Carolina.
Software manual
SAS Institute, Inc. 2001. SAS/STAT Guide for Personal Computers, Version
8. Cary, NC:SAS Institute, Inc.
Website
U.S. EPA (U.S. Environmental Protection Agency). 2004. Integrated Risk
Information System. Available: http://www.epa.gov/iriswebp/iris/ [accessed
1 October 2004].
Abstract
Levin E, Simon B, Schmechel D, Glasgow HB Jr, Deamer-Melia N, Burkholder
J, et al. 1998. Learning deficits in rats after Pfiesteria exposure
[Abstract]. Toxicol Sci 42:37.
Federal regulation
U.S. EPA. 1998. National Primary Drinking Water Regulations: Interim Enhanced
Surface Water Treatment; Final Rule. Fed Reg 63:69477–69521. Emission
Guidelines and Compliance Times for Hospital/Medical/Infectious Waste
Incinerators. 2001. Waste Management Guidelines. 40CFR60.35e.
Executive order; federal regulation
Clinton WJ. 2000. Executive Order 13148. Greening of the Government Through
Leadership in Environmental Management. Fed Reg 65:24595–24606.
U.S. government document
U.S. EPA. 1999. What You Should Know about Fish Lesions. CBP/TRS229/99.
Washington, DC:U.S. Environmental Protection Agency.
State document
State of Maryland. 1998. Water Quality Improvement Act of 1998. Annapolis,
MD:General Assembly.
Law
Food Quality Protection Act of 1996. 1996. Public Law 104-170.
Court case
Les v. Reilly. 1992. Case No. 91–70234, U.S. Court of Appeals for
the Ninth Circuit, San Francisco, CA.
Tables
Each table must begin on a separate page. Tables should be numbered with
Arabic numerals, followed by a brief title (not to exceed 25 words). When
setting up tables, do not use table layouts; type tables as text and use
tabs to align the columns. Tables should contain no more than three layers
of column headings, and the entire table should fit on one journal page
or less. List abbreviations and definitions under each table. General footnotes
to tables should be indicated by lowercase superscript letters beginning
with “a” for each table. Footnotes indicating statistical significance
should be identified by asterisks
(*, **) and number signs (#, ##). Type footnotes
directly after the abbreviations.
Figures
Figure legends should be typed on one page using Microsoft Word; this page
should precede the figures and be submitted electronically in a single
file at the end of the text. If you have questions or problems complying
with these instructions, contact EHP.
All letters, numbers, symbols, and lines should be clearly legible and
differentiable. Provide a key defining all representational elements (dotted/dashed
lines, symbols, asterisks, error bars, etc.) for each figure. All axes
should be clearly labeled, giving both the measure and the unit of measurement
where applicable. No lines of demarcation or measurement should appear
inside the graph itself, only on the axes. Consistency among terms and
styles used in figures is desirable. Photomicrographs should include a
scale bar in each image, and the length (e.g., 10 µm) should be specified
in the typed figure legend.
Format
Checklist
Manuscripts should include these sections in this order:
Title
Authors’ affiliations
Name and address of corresponding author
Acknowledgments/disclaimers
Short running head
Key words
Outline of manuscript section headers
Introduction
Results
Conclusions
Tables
Figures
Material suitable for inclusion as online documentation, such as kinetic
studies, is welcome. Contact the
EHP editors for instructions
regarding submission.
Submission
of Manuscripts
Initial Submission
A single PDF should be sent including text, tables,
and figures, with particular attention paid to minimizing
and optimizing graphics (i.e., image size includes
file dimensions and resolution). File size should not
exceed 5 MB, preferably less than 1 MB. Graphics must
fit standard letter size paper (8.5 
11
inches) or smaller. Line graphs generally provide acceptable
images at 72–100 dpi. Photographs seldom require > 300
dpi; if optimized generally 100 dpi is acceptable.
(Higher resolution images of photographs will be required
if manuscript is accepted for publication.) Figures
must be identifiable in the PDF file. If there are
questions about preparing PDF files, please contact
the journal.
Manuscripts may be submitted in one of four ways:
-
-
E-mail the manuscript file, the competing financial
interest form, and a separate cover letter to:
EHPSubmit@niehs.nih.gov
-
Submit the PDF file, the competing financial interest
form, and the cover letter via the FTP server. Software is available
free of charge over the Internet. For Windows PC users, go to
http://www.tucows.com/preview/195124.html.
For Macintosh users, go to
http://fetchsoftworks.com/.
An FTP server is available at
ehpdrop.niehs.nih.gov for
materials receipt and transfer at the
EHP editorial office:
User name: EHPauthor
Password: the user’s e-mail address.
- Mail one hard copy of the cover letter, the competing financial interest
form, the
manuscript, and a disc (3.5 inch floppy, CD, or zip) with the electronic
version to:
Editor-in-Chief--for submissions
to the monthly and Chinese-Language editions Toxicogenomics
Editor--for submission to the Toxicogenomics
Section
Children’s Health Editors--for submission to the Children’s
Health Section
Medical Editor--for submission to the Environmental Medicine Section
Environmental Health Perspectives
National Institute of Environmental Health Sciences
Mail Drop EC-15
PO Box 12233
79 Alexander Drive
4401 Building, Room 3102
Research Triangle Park, NC 27709
USA
If you do not have access to Acrobat software, you may submit your manuscript
as a Word file; we will convert the file to PDF. However, because of potential
conversion problems, we cannot guarantee complete accuracy in the electronic
copy that is sent for review.
Online submission of papers will expedite the entire review process between
authors, expert reviewers, and EHP editors. Authors may continue to
submit papers to EHP by one of the other three methods, but processing
will necessarily be slower.
Submission of Revised Manuscript
After the review process is completed, EHP will e-mail the
corresponding author the reviewer’s comments. If EHP requests
revisions or accepts the manuscript at this point, please submit all of
the following:
-
All text, tables, and figure legends in one electronic
file (Microsoft Word). Make sure that any symbols and/or equations correctly
appear on printed copies and that that all figures and tables are called
out in the body text in numerical order
-
Each figure as a separate file at 300 dpi, TIFF, JPEG,
or EPS format. Do not embed figures in word processing file (see
below for specific figure formats)
-
A PDF file that includes the entire manuscript with
all tables and figures (see the EHP-in-Press distiller preferences
below). Each figure must be labeled on the front with the figure number. This
is the file that will be published online if the manuscript is accepted.
It will be published exactly as you submit it. No copyediting or manipulating
of the file will be done at EHP
-
A cover letter with responses to the reviewers’ comments
-
Three hard copies of the manuscript and figures.
Online submission of revised manuscripts is strongly encouraged. You will
also need to mail three hard copies of the manuscript and figures to EHP.
OR
Mail three hard copies of the cover letter, manuscript and figures with
a disc(s) (floppy, zip, or CD) with all of the electronic files. Please
label the disc with your last name, the title of the manuscript, the EHP manuscript
number and the operating system and word processing software versions used.
Figure Format Requirements (for Revised Manuscripts)
Format all figures in Macintosh format (if possible) and indicate the type
of software used to create the figures.
Electronic images should be in TIFF or JPEG format at a resolution of
300 dpi or higher for color and grayscale images, and 600 dpi or higher
for line art (black-and-white art). JPEG files should be saved on the “highest
quality” setting. Color images should be RGB and saved at 8 bits
per channel, minimum. Figures may be reduced or enlarged to fit our layouts,
so sufficient resolution is essential.
Vector images should be saved as editable EPSs. Any images embedded in
the EPS should also be included on the disk in a separate file. Do not
convert text to path outlines before submission.
Required Cover Letter
In your cover letter, identify the EHP edition (monthly or Chinese-Language)
or EHP section (Mini-Monograph, Environmental Medicine, Toxicogenomics,
or Children’s Health) for which the manuscript should be considered.
Also please provide:
-
Assurances that the manuscript is a) an original
work, b) has not been previously published, and c) is
not under consideration for publication elsewhere
-
A statement that all animals used in the research
have been treated humanely according to institutional guidelines, with
due consideration to the alleviation of distress and discomfort; the
identity of the source of those guidelines must be provided
-
A statement that participation of human subjects did
not occur until after informed consent was obtained
-
Confirmation that all authors have disclosed any potential
competing financial interests regarding the submitted article and what
they are (required Competing Financial Interest Declaration form:
http://ehp.niehs.nih.gov/cfi.pdf)
-
Written permission from copyright holder (usually
the publisher) to reproduce figures, tables, questionnaires,
or a substantial block of text in both print and electronic form
-
A statement indicating that a) all authors
have read the manuscript, b) agree that the work is ready for
submission to a journal, and c) they accept responsibility for
the manuscript’s contents
-
The names of possible reviewers for the manuscript,
including e-mail addresses of the potential reviewers
-
Information on the software programs used, the file
names, and the number of tables and figures for each submission (see “Files
and Formats” for electronic file requirements). Inquiries may
be made by calling 919-541-3406 or by sending a fax to 919-541-0273.
Manuscript Processing
All manuscripts will be sent to three expert reviewers and returned
to EHP by electronic transmission to accelerate the peer
review process. After editorial consideration, a decision letter and
reviewers’ comments will be e-mailed to authors.
Be aware that, if the revised article is accepted, the PDF version will
be published online within 24 hours of acceptance (http://www.ehponline.org).
After acceptance, the PDF version will be assigned a completely citable
DOI (Digital Object Identifier) code. The PDF file of the article will
be included in the EHP-in-Press section of our website.
Electronic material will be converted at EHP to a desktop publishing
format and copyedited. The copyedited version, with embedded author queries,
will be converted to a PDF version for electronic transmission of page
proofs to authors. The authors can use free Acrobat Reader software (http://www.adobe.com/products/acrobat/alternate.html),
available over the Internet, to proof the material.
Authors should return corrected page proofs by fax or overnight mail.
A list of itemized changes and their locations must accompany the page
proofs or be sent by e-mail.
The PDF version of the EHP-in-Press articles will be replaced with
the copyedited and stylized version as soon as possible but, importantly,
the DOI code will remain with the copyedited article. In addition to the
DOI code, the copyedited article will have assigned volume and page numbers
that will allow full conventional citation. The final versions may be slightly
different as a result of the editing process but there will be no substantive
changes allowed. Any substantive changes at this stage will require an
erratum to be published.
Articles will be published in the print version in order of acceptance
as journal space permits.
Acrobat Distiller Preferences for Preparing PDFs
for EHP-in-Press
Software Required: Adobe Acrobat Distiller 5.0 or later
Security Settings: Passwords should not be set in the document.
Permissions (the following should be checked):
Enable Content Access for the Visually Impaired
Allow Content Copying and Extraction
Changes Allowed: General Editing, Command and Form
Field Authoring
Job Options:
Compatibility: Acrobat 5.0 (PDF 1.4)
Optimized For Fast Web View
Distill Pages: All
Resolution: 300 dpi
Units: Inches
Height: 11
Color Images:
Bicubic Downsampling to 300 dpi for images above
450 dpi
Quality: Medium
Bicubic Downsampling to 300 dpi for images above
450 dpi
Quality: Medium
Bicubic Downsampling to 300 dpi for images above
450 dpi
Compression: CCITT Group 4
Compress Text and Line Art (checked)
Embed All Fonts
Subset Embedded Fonts When Percent of Characters Used is Less Than 100%
Color:
Settings File: U.S. Prepress Defaults
Device-Dependent Data:
Preserve Overprint Settings
Preserve Under Color Removal and Black Generation
Preserve Transfer Functions
Advanced (only check the following options):
Allow PostScript File to Override Job Options
Preserve Level 2 copypage Semantics
Illustrator Overprint Mode
Convert Gradients to Smooth Shades
Document Structuring Conventions (DSC):
Process DSC Comments
Resize Page and Center Artwork for EPS Files
Preserve Document Information from DSC
