American Dad!: Francine. With her high energy, she can be somewhat crazy.
Batman: Caped Crusader averts this with Harley Quinn, who's a very stoic and serious character. It's played straight with her Harleen Quinzel persona where, while she tries acting professional, still shows a good deal of enthusiasm and gung ho spirit when interacting with others.
Batman: The Animated Series: Harley Quinn displays this quite a bit with her eagerness to please the Joker, and her general childish enthusiasm in trying to take down the heroes.
Daria: Brittany. She's a bubbly, energetic, and ditzy blonde-haired Girlish Pigtails-wearing cheerleader who just wants to make people happy. There are other examples on the show as well. Quinn lapses into this at times. Stacey maybe even more so.
FETCH! with Ruff Ruffman: Season 2's Rosario Corso is a male example. He's usually very funny in the show, and the episode "Ruff's Big Break" goes to show just how hilarious he can be.
In "Don't Like Fencing, Try Fencing!" Ruff first describes Season 4 contestant Liza who ""goes bananas for bananas".
Gargoyles introduced Puck in "The Mirror", a trickster elf of the Third Race. A bit more subdued than most examples, he is still one of the most energetic characters in the show; constantly floating or dancing around, befitting his carefree nature.
Glitch Techs: Miko's one boisterous tomboy. Even while playing games, she tends to move and run around constantly.
Goof Troop: Pistol is constantly hyper. As her neighbor Max once put it, "watching Pistol is like nailing Jell-O to a tree." Playing with her is considered a nuisance at best and outright torture at worst, and, if they can, people try to avoid the task or pass it on to others, usually stopping at Extreme Doormat PJ unless he manages to hide. It's fairly surprising, considering that her father is very lazy and her mother and brother take turns being the Only Sane Man.
Gravity Falls: Mabel Pines is loud, playful, and enthusiastic about just about everything ("Yay, grass!"). Her energy is justified since the show has frequent references to her sugar intake.
Wendy: What is she talking about?
Dipper: Nothing! Mabel's just been eating raw sugar packets again.
Mabel: (Eating sugar packets) Om nom nom... that's beside the point!
Charlie Morningstar is a peppy and enthusiastic demon princess who's all fired up about the idea of rehabilitating demons and sending them to Heaven. Sometimes aggressively so.
Charlie: Omigosh, welcome to the Happy Hotel! You are going to LOVE IT HERE!!
Niffty the maid is very hyperactive and zips around the hotel at incredible speed.
Sara Snap is definitely a feisty ball of energy whenever she's passionate about something, such as lifting heavy objects, or her sports idol Athletica.
Turbo Tina also falls into this thanks to her speed and Motor Mouth tendencies when she's excited.
Hi Hi Puffy AmiYumi: Ami Onuki, who's very much this. Excitable, cheerful, always optimistic, and an all-around sweetie. Needless to say, whenever Ami gets all excited, she sometimes gets on Yumi's nerves as a result. For example, in "Collect All Five", there's this little exchange when Ami explains to Yumi about the Super Rainbow Blast cereal:
Ami: Isn't it awesome?!
Yumi: Yeah, awesomely sappy.
A number of characters (female andmale) in Jellystone! have shades of this, but the one character who fully embodies the trope is the show's version of Jabberjaw.
Jabberjaw: Anybody wanna hear how loud I can scream? AAAAAAAAAH!!!
KaBlam!: June started out as one of these, as well as The Ditz. In season two, she's still this trope at times, but much more snarky. In season three, this starts to drop a little bit more as she becomes a sarcastic Jerkass, and by season four, this is gone and she became a slight example of the only sane girl.
Kaeloo is perpetually cheerful, hyperactive, playful, and enthusiastic about almost everything.
The Loud House: Leni, Luan, and Lily are very happy-go-lucky, Lynn is energetic enough to do many sports at once, and Luna is a rocker. Darcy also seems quite cheery, although she does cry when Lisa rejects her. Sid is also very upbeat and energetic and Polly Pain is energetic too.
The Mighty B!: Bessie Higgenbottom is an ambitious and optimistic 9-year-old Honeybee Scout who believes that she will become a superhero called "The Mighty B" if she collects every Honeybee badge.
Molly of Denali: Molly is a playful, happy-go-lucky girl. She loves coming up with crazy schemes and going on epic adventures.
My Life as a Teenage Robot: Jenny is very bubbly and is shown to get excited easily. Her mother is also is very excitable and lively, so it's no surprise where she gets it from.
Pinkie Pie is this merged with Cloudcuckoolander. Her energy breaks the fourth wall by pure accident! "Party of One" explores (and later deconstructs) this; there is a limit to her energy, but it is significantly higher than everyone else's. Then you watch her get angry and find out her energy can be used for more than just bouncing happily... "Too Many Pinkies" has Pinkie inadvertently creating an unruly horde of flanderized clones of herself. Her friends, used to Pinkie embodying this trope, can't tell the difference between the mindless clones who constantly spout "FUN!" and the real Pinkie. This causes Pinkie to have an existential crisis and seriously consider the possibility that she's just a clone who thinks she's real.
The Cutie Mark Crusaders. Individually, they're energetic. Together, they egg each other on and build off each other to astonishing lengths.
Rainbow Dash counts as well, especially in later episodes with her excitement over the new Daring Do book and the Equestria Games. Often fills this role throughout the series when Pinkie Pie isn't present.
As "Amending Fences" reveals, Minuette, one of Twilight's old Canterlot friends, is a very upbeat girl. No wonder she and Pinkie are friends.
Gabby Griffon is a griffon who's obsessed with getting a cutie mark of her own (despite it being a pony-only trait) and a major glomp. Even the Cutie Mark Crusaders find her energy overwhelming.
Silverstream the Hippogriff is absolutely fascinated by everything on the surface world after she spent most of her life in a coral reef underwater.
One-shot character Autumn Blaze may be an even bigger Motor Mouth than Pinkie Pie. Given that her fellow Kirin decided to stop talking, it's not surprising she'd have a lot to say.
Mysticons: Piper is extremely energetic, often doing acrobatic moves (such as flips) and having some pretty energetic responses when she figured out a riddle or if she's excited.
Numberjacks: A lot of characters seem to fit this trope, but Three is the most recognisable example. Getting jumpy and excited, especially when she's going out on missions. Is it any wonder Four, Five, and Six sometimes consider her a handful?
Phineas and Ferb: Candace Flynn can fall into this when she's excited about something that doesn't involve busting Phineas and Ferb. Her energy levels can rival her brothers to say the least.
The Powerpuff Girls: Bubbles is, fittingly enough, the most bubbly of the girls, having their "joy and the laughter".
Rita Raspberry from Princess Power is the most energetic and enthusiastic princess in the Princess Pack with how she's always excited to take on anything.
Puppy Dog Pals has two girl pups Keia and Lollie who are both very energetic.
Recess: Cindy, one of the kindergartners, is very energetic and full of life. Miss Grotke can be a mild example at times since she tends to be more optimistic than the other teachers.
Rolie Polie Olie has Zowie, the younger sister of the titular Olie. Most child characters in the series are cheerful children, but she easily takes the cake by being the most hyperactive and rambunctious out of all of them. She is outgoing and welcoming to nearly everyone she meets, and often happily cries "Olie Olie Olie Olie!" whenever her brother comes into the picture.
Sofia the First: In stark contrast to her owner, who is shy when Sofia first meets her, Crackle is an excitable dragon who likes tackle-hugging any new friend she meets, especially Clover.
Star vs. the Forces of Evil: Star Butterfly, who takes this as far as the meter goes and more. She is a hyperactive teenage girl whose hobbies include fighting monsters, going on dangerous adventures, and using her wand's powers to create anything she wants, such as adorable animals or indoor water slides.
Super Best Friends Forever: Batgirl fits this trope with how she's often enthusiastic and full of joy about anything involving superheroics.
Teen Titans (2003): Starfire. All that emotional energy is the source of her superpowers. 'Joy' for Flight, 'confidence' for super strength, and general perkiness.
Izzy. So genki, that she's even enthusiastic about getting poison ivy wrapped around her face as part of a challenge.
Sierra is almost as hyper and energetic as Izzy, further exacerbated by her fangirliness.
Lindsay also counts as well. She's really bubbly and energetic, and tends to get excited if she sees something she likes. She's really cheerful and, despite being a Dumb Blonde, always makes up for her mistakes with her positive attitude and kind-hearted personality.
Transformers: Prime: Miko, who transferred to an American school to escape a life of piano lessons and ends up in the middle of a war between alien robots, to her absolute delight. She's voiced by Tania Gunadi, who is good at these in many of her roles.
Ava Banji from Unicorn Academy fits the bill. She's incredibly giddy, enthusiastic, and friendly when she tries helping others, and caring for animals and nature.
