On Fedora Silverblue 37 I tried:
sudo rpm-ostree install python3-pip
but it failed.

Here's a workaround that works for Silverblue 37:

git clone https://github.com/shotgunsoftware/python-api.git sgpythonapi
cd sgpythonapi/
sudo python3 setup.py install

I'm able to create sg and do sg.find()/sg.find_one() after that.