diff --git a/CHANGELOG.md b/CHANGELOG.md
index 62caf93..bec84af 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,12 @@
 # Changelog
 
+## [1.4.3](https://github.com/googleapis/python-resource-settings/compare/v1.4.2...v1.4.3) (2022-10-07)
+
+
+### Bug Fixes
+
+* **deps:** Allow protobuf 3.19.5 ([#143](https://github.com/googleapis/python-resource-settings/issues/143)) ([b253cf5](https://github.com/googleapis/python-resource-settings/commit/b253cf5723a8fe5a43b350bb1d177bea34a7084a))
+
 ## [1.4.2](https://github.com/googleapis/python-resource-settings/compare/v1.4.1...v1.4.2) (2022-09-29)
 
 
diff --git a/setup.py b/setup.py
index 6906c6d..ffff9d1 100644
--- a/setup.py
+++ b/setup.py
@@ -20,7 +20,7 @@
 
 import setuptools  # type: ignore
 
-version = "1.4.2"
+version = "1.4.3"
 description = "Resource Settings API client library"
 package_root = os.path.abspath(os.path.dirname(__file__))
 
@@ -44,7 +44,7 @@
     install_requires=(
         "google-api-core[grpc] >= 1.32.0, <3.0.0dev,!=2.0.*,!=2.1.*,!=2.2.*,!=2.3.*,!=2.4.*,!=2.5.*,!=2.6.*,!=2.7.*",
         "proto-plus >= 1.22.0, <2.0.0dev",
-        "protobuf >= 3.20.2, <5.0.0dev",
+        "protobuf>=3.19.5,<5.0.0dev,!=3.20.0,!=3.20.1,!=4.21.0,!=4.21.1,!=4.21.2,!=4.21.3,!=4.21.4,!=4.21.5",
     ),
     python_requires=">=3.7",
     classifiers=[
diff --git a/testing/constraints-3.7.txt b/testing/constraints-3.7.txt
index df8564d..4005dc5 100644
--- a/testing/constraints-3.7.txt
+++ b/testing/constraints-3.7.txt
@@ -6,4 +6,4 @@
 # Then this file should have google-cloud-foo==1.14.0
 google-api-core==1.32.0
 proto-plus==1.22.0
-protobuf==3.20.2
+protobuf==3.19.5