What steps will reproduce the problem?
1.i start cfg loader and click the game and start, it just freezes and need to 
off and on it again
2.even while playing metroid it just freeze randomly 
3.

What is the expected output? What do you see instead?
just normally game starts and can be played normally but when sometimes it 
loads the game but while im playing the game it freezes.

What version of the loader are you using?

70
What is your System Menu version (e.g. 4.2u)?
4.3k

What is your media type (HDD, USB Flash, SD/SDHC)?

hdd WD350 gb
How is your media formatted (wbfs, fat32, ntfs)?

wbfs
Which cios are you using, which version, which base (222,249,...)?
(Please try both 249 and 222 with cfg-222.dol)
tried 248,249 and 250

Does it work with other loaders?
didn't try

Does it work with the latest or an older version?

no
Please provide any additional information below.
 when i click start, it freezes with white start button