Dihydrothymine
Appearance
| Names | |
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| IUPAC name
5-methylhexahydropyrimidine-2,4-dione | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
| ECHA InfoCard | 100.010.717 |
| MeSH | 5,6-dihydrothymine |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C5H8N2O2 | |
| Molar mass | 128.131 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Dihydrothymine is an intermediate in the metabolism of thymine. The enzyme dihydrouracil dehydrogenase (NAD+) converts thymine to dihydrothymine in the reaction:[1][2]
References
[edit]- ↑ Campbell LL (August 1957). "Reductive degradation of pyrimidines. III. Purification and properties of dihydrouracil dehydrogenase". The Journal of Biological Chemistry. 227 (2): 693–700. doi:10.1016/S0021-9258(18)70749-7. PMID 13462991.
- ↑ West, Thomas P. (2001). "Pyrimidine base catabolism in Pseudomonas putida biotype B". Antonie van Leeuwenhoek. 80 (2): 163–167. doi:10.1023/A:1012275512136. PMID 11759049.
