PBT assessment list

ECHA’s persistence, bioaccumulation and toxicity (PBT) assessment list includes the substances undergoing a PBT/vPvB assessment that have been brought for discussion to ECHA’s PBT Expert Group.

Explanatory note

Inclusion in the list means that an informal hazard assessment for PBT/vPvB properties either is under development or has been completed since February 2013.

For each substance, the table shows the assessing or evaluating Member State (submitter), the outcome from the assessment, and the date of the latest update to the list entry.

Other process details and hazard assessment outcome documents are also available and can be accessed through the ‘Details’ icon.

One possible outcome of such an assessment is that a substance is considered not to have PBT/vPvB properties.

If the outcome is that the substance is considered to have PBT/vPvB properties, confirmation through the formal risk management and decision-making processes is needed before any regulatory action can be taken due to these properties.

The intentions of authorities to submit a dossier to the formal REACH and CLP processes are notified through the Registry of Intentions. All biocidal active substances have to undergo a formal PBT assessment. You can see the status of biocides assessments on the Biocidal Active Substances page.

Disclaimer

The information and views set out in the PBT assessment list and in the hazard assessment outcome documents are those of the evaluating authority and do not necessarily reflect the position or opinion of the other Member States or ECHA. Neither ECHA nor the evaluating authority nor any person acting on either of their behalves may be held liable for the use, which may be made of the information contained therein. Statements made or information contained in the documents are without prejudice to any formal regulatory activities that ECHA or the Member States may initiate at a later stage. PBT assessments and their outcomes are compiled on the basis of information available by the date of the publication of the document.

Last updated 07 November 2025. Database contains 245 unique substances/entries.

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Latest update:

Outcome:

Date of intention:

Date of hazard assessment:

Showing 1 - 50 of 255 results.

Substance name	EC / List no	CAS no	Authority	Outcome	Latest update
N-(1,4-dimethylpentyl)-N'-phenylbenzene-1,4-diamine	221-374-3	3081-01-4	Austria	inconclusive	07-Nov-2025	Details
Benzene, C10-13-alkyl derivs.	267-051-0	67774-74-7	Italy	inconclusive	07-Nov-2025	Details
Phenol, styrenated	262-975-0	61788-44-1	Germany	Under development	31-Oct-2025	Details
Dioctyltin oxide	212-791-1	870-08-6	Austria	Under development under SEV	31-Oct-2025	Details
3-phenoxybenzyl-2-(4-ethoxyphenyl)-2-methylpropyl ether ETHOFENPROX; TREBON	407-980-2	80844-07-1	Austria	inconclusive	23-Oct-2025	Details
tert-butyl methyl ether	216-653-1	1634-04-4	France	Under development	11-Sep-2025	Details
Dimethylsilanediol	213-915-7	1066-42-8	Norway	Under development	11-Sep-2025	Details
Dichloro(dimethyl)silane	200-901-0	75-78-5	Norway	Under development	11-Sep-2025	Details
2-methoxy-2-methylbutane	213-611-4	994-05-8	France	Under development	11-Sep-2025	Details
2-ethoxy-2-methylpropane	211-309-7	637-92-3	France	Under development	11-Sep-2025	Details
2-ethoxy-2-methylbutane	618-804-0	919-94-8	France	Under development	11-Sep-2025	Details
Oligomerisation products of alpha-pinene and beta-pinene	701-463-8	-	Spain	Under development under SEV	04-Sep-2025	Details
O,O,O-triphenyl phosphorothioate	209-909-9	597-82-0	Netherlands	PBT	12-Jun-2025	Details
Trade name: 3M(TM) NOVEC(TM) ENGINEERED FLUID HFE-7000	484-450-7	1610350-01-0	Spain	vPvM	05-Jun-2025	Details
2-Ethoxy-3,3,4,4,5-pentafluoro-2,5-bis[(1,2,2,2-tetrafluoro-1-trifluoromethyl)ethyl] tetrahydrofuran	484-410-9	920979-28-8	Spain	vPvM	05-Jun-2025	Details
1,1,1,2,2,3,3,4,4-nonafluoro-4-methoxybutane; 1,1,1,2,3,3-hexafluoro-3-methoxy-2-(trifluoromethyl)propane	422-270-2	163702-08-7	Spain	PMT	05-Jun-2025	Details
Reaction mass of 2,6-bis(1-phenylethyl)phenol and 2,4,6-tris(1-phenylethyl)phenol	701-171-0	-	Germany	not PBT not vPvB	23-Apr-2025	Details
Reaction products of acetic anhydride and 1,5,10-trimethyl-1,5,9-cyclodecatriene	482-330-9	144020-22-4	Austria	postponed	26-Feb-2025	Details
Hexamethyldisiloxane	203-492-7	107-46-0	Norway	not PBT not vPvB	26-Feb-2025	Details
1-(4-chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-ylmethyl)pentan-3-ol TEBUCONAZOLE RESP. HWG 1608	403-640-2	107534-96-3	Denmark	not PBT not vPvB	26-Feb-2025	Details
1,1'-(methylenedi-4,1-phenylene)bis(3-butylurea)	416-600-4	-	France	not PBT not vPvB	26-Feb-2025	Details
reaction mass of mixed (3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) phosphates, ammonium salt	700-161-3	-	Netherlands	PBT vPvB PMT vPvM	30-Jan-2025	Details
1,4-Benzenediamine, N,N'-mixed tolyl and xylyl derivs.	270-820-3	68478-45-5	Germany	inconclusive	27-Jan-2025	Details
1,4-Benzenediamine, N,N'-mixed Ph and tolyl and xylyl derivs.	273-226-2	68953-83-3	Germany	inconclusive	20-Jan-2025	Details
4,4'-methylene bis(dibutyldithiocarbamate)	233-593-1	10254-57-6	Germany	vPvB	15-Jan-2025	Details
Sodium 3-(2H-benzotriazol-2-yl)-5-sec-butyl-4-hydroxybenzenesulfonate BENZTRIAZOL UV ABSORBER BUK 4499; BUK 4499; UV ABSORBER BUK 4499	403-080-9	92484-48-5	Spain	Under development under SEV	09-Jan-2025	Details
reaction mass of: ethyl (2R,3R)-3-isopropylbicyclo[2.2.1]hept-5-ene-2-carboxylate; ethyl (2S,3S)-3-isopropylbicyclo[2.2.1]hept-5-ene-2-carboxylate	427-090-8	116044-44-1	Netherlands	Under development	09-Jan-2025	Details
Reaction mass of p-t-butylphenyldiphenyl phosphate and bis(p-t-butylphenyl) phenyl phosphate	939-505-4	-	France	Under development under SEV	09-Jan-2025	Details
Phenol, isopropylated, phosphate (3:1)	273-066-3	68937-41-7	Netherlands	Under development under SEV	09-Jan-2025	Details
Methyl-1H-benzotriazole	249-596-6	29385-43-1	Germany	PMT vPvM	09-Jan-2025	Details
Melamine	203-615-4	108-78-1	Germany		09-Jan-2025	Details
Bis(4-chlorophenyl) sulphone	201-247-9	80-07-9	Austria	vPvB	09-Jan-2025	Details
Bis(2-ethylhexyl)amine	203-372-4	106-20-7	Portugal	Under development under SEV	09-Jan-2025	Details
Bis(2-ethylhexyl) tetrabromophthalate	247-426-5	26040-51-7	Sweden	vPvB not PBT	09-Jan-2025	Details
Benzotriazole	202-394-1	95-14-7	Germany		09-Jan-2025	Details
A mixture of: dicalcium (bis(2-hydroxy-5-tetra-propenylphenylmethyl)methylamine)dihydroxide; tri-calcium (tris(2-hydroxy-5-tetra-propenylphenylmethyl)methylamine)tri-hydroxide; poly[calcium ((2-hydroxy-5-tetrapropenyl-phenylmethyl)methylamine)hydroxide] OLOA 224 (OIL FREE)	420-470-4	-	Spain	inconclusive	09-Jan-2025	Details
4,4'-Methylene-bis-(3-chloro-2,6-diethylaniline)	402-130-7	106246-33-7	Netherlands	Under development	09-Jan-2025	Details
N,N'-ethylenebis(3,4,5,6-tetrabromophthalimide)	251-118-6	32588-76-4	Norway	inconclusive	19-Dec-2024	Details
2-[(4-methoxy-2-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide	229-419-9	6528-34-3	Italy	inconclusive	19-Dec-2024	Details
tert-butyl methyl ether	216-653-1	1634-04-4	France	vPvM	17-Dec-2024	Details
Bis(isopropyl)naphthalene	254-052-6	38640-62-9	Sweden	vPvB	28-Nov-2024	Details
Imidazolium compounds, 2-C17-unsatd.-alkyl-1-(2-C18-unsatd. amidoethyl)-4,5-dihydro-N-methyl, Me sulfates	931-745-8	-	Sweden	not PBT not vPvB	21-Nov-2024	Details
Bis(α,α-dimethylbenzyl) peroxide	201-279-3	80-43-3	Norway	not PBT not vPvB	12-Nov-2024	Details
1,1'-(ethane-1,2-diyl)bis[pentabromobenzene]	284-366-9	84852-53-9	Sweden	vPvB not PBT	12-Nov-2024	Details
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine SR-245	426-040-2	25713-60-4	Netherlands	not PBT	31-Oct-2024	Details
Reaction mass of 3,6-Bis(3-chlorophenyl)-2,5-dihydro-pyrrolo[3,4-c]pyrrole-1,4-dione, 3-(3-Chlorophenyl)-6-(4-chlorophenyl)-2,5-dihydro- pyrrolo[3,4-c]pyrrole-1,4-dione and 3,6-Bis(4-chlorophenyl)-2,5-dihydro-pyrrolo[3,4-c]pyrrole-1,4-dione	465-080-5	-	Germany	Under development	03-Oct-2024	Details
ORANGE IRGAPHOR 502A	424-920-0	-	Germany	Under development	03-Oct-2024	Details
Experimental Rubine 4013 M	472-070-4	-	Germany	Under development	03-Oct-2024	Details
3-(biphenyl-4-yl)-6-(4-chlorophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione	700-341-1	-	Germany	Under development	03-Oct-2024	Details
3,6-Bis-biphenyl-4-yl-2,5-dihydro-pyrrolo[3,4-c]-pyrrole-1,4-dione	413-920-6	88949-33-1	Germany	Under development	03-Oct-2024	Details

Showing 1 - 50 of 255 results.

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